![]() The median length-of-stay was 7 (IQR 6–10) days. Cox models were used to assess the association of outcomes with BP during hospitalization. The primary and secondary outcomes were all-cause death and cardiac death, respectively. The average BP on the first seven days of hospitalization was categorized into 10-mmHg increments. ![]() We aimed to analyze the associations between BP control in the first 7 days of hospitalization and long-term mortality specific to patients with isolated left ventricular MI.Ī total of 3108 acute left ventricular MI patients were included in this analysis. Acute left ventricular MI is a prevalent type of AMI with poor prognosis. Previous studies have shown that optimal blood pressure (BP) control is necessary to outcomes in patients with acute myocardial infarction (AMI). Analyzing data from multiple measurements and identifying different categories of patient populations with sepsis will help identify the risks among these categories. Maintaining a systolic blood pressure of approximately 140 mmHg in patients with sepsis within 10 h of admission was associated with a lower risk of in-hospital mortality. Subgroup analysis indicated that a nominal interaction occurred between age group and blood pressure trajectory in the in-hospital mortality (P < 0.05). Univariate and multivariate Cox regression analysis indicated that, with class 1 as a reference, patients in class 2 had the highest in-hospital mortality risk (P < 0.001). The K-M analysis indicated that patients in class 2 had the lowest probability of survival. Seven different SBP trajectories were identified based on model-fit criteria. ![]() The median survival time was 67 years (interquartile range: 56-77 years). This study included 3034 patients with sepsis. ![]() The survival probability of different trajectory groups was investigated using Kaplan-Meier (K-M) analysis, and the relationship between different SBP trajectories and in-hospital mortality risk was investigated using Cox proportional-hazards regression model. The SBP measured ten times after admission was analyzed using latent growth mixture modeling to construct a trajectory model. Ten SBP values within 10 h after hospitalization were extracted, and the interval between each SBP value was 1 h. However, few studies have measured the systolic blood pressure (SBP) multiple times and established trajectory models for patients with sepsis with different SBP trajectories.ĭata from patients with sepsis were extracted from the Medical Information Mart for Intensive Care-III database for inclusion in a retrospective cohort study. Numerous studies have investigated the mean arterial pressure in patients with sepsis, and many meaningful results have been obtained. ![]()
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